Place the beef stew meat in the bottom of the slow cooker.
Add the butternut squash, onion, carrots, and garlic on top of the beef.
Pour the beef broth over the ingredients.
Sprinkle the salt, black pepper, and fresh sage across the top.
Stir once to distribute the seasonings evenly.
Cover and cook on low for 8 hours or on high for 4 hours until the beef is fork-tender.